硕士生导师简历
基本信息
姓名: 王印虎
职称: 讲师
学历: 博士
电话:18954545955
电子信箱:wangyinhuabc@126.com
出生年月:1988.07
研究方向: 抗菌药物研究
毕业学校: 山东大学
职务: 无
研究工作简介
基于靶点(例如,AcrB和抗菌肽模拟物等)的抗耐药菌小分子化合物的设计、合成、抗菌活性和抗耐药机理研究。
发表论文(按时间倒序排列)
(1) Yinhu Wang#, Rawaf Alenazy#, Xinjie Gu, Steven W Polyak, Panpan Zhang, Matthew J Sykes, Na Zhang, Henrietta Venter*, Shutao Ma*. Design and structural optimization of novel 2H-benzo[h]chromene derivatives that target AcrB and reverse bacterial multidrug resistance. European Journal of Medicinal Chemistry, 2021, 213, 113049.
(2) Yinhu Wang#, Rawaf Alenzy#, Di Song, Xingbang Liu, Yuetai Teng, Rumana Mowla, Yingang Ma, Steven W. Polyak, Henrietta Venter*, Shutao Ma*. Structural optimization of natural product nordihydroguaretic acid to discover novel analogues as AcrB inhibitors. European Journal of Medicinal Chemistry, 2020, 186, 15, 111910.
(3) Yinhu Wang# **, Chen Qu#, Tingting Liu, Chunhui Wang*. PFKFB3 inhibitors as potential anticancer agents: Mechanisms of action, current developments, and structure-activity relationships. European Journal of Medicinal Chemistry, 2020, 203, 112612.
(4) Yinhu Wang#, Rumana Mowla#, Liwei Guo, Miguel A. De Barros Lopes, Chaobin Jin, Di Song, Shutao Ma* & Henrietta Venter*. Design, synthesis and biological activity evaluation of novel 4-subtituted 2-naphthamide derivatives as AcrB inhibitors. European Journal of Medicinal Chemistry, 2018, 43, 1: 699-709.
(5) Yinhu Wang, Chao Cong, Wern Chern Chai, Ruiqian Dong, Li Jia, Di Song, Ziteng Zhou, Shutao Ma*. Synthesis and antibacterial activity of novel 4"-O-(1-aralkyl-1,2,3-triazol-4-methyl-carbamoyl) azithromycin analogs. Bioorganic & Medicinal Chemistry Letters, 2017, 27: 3872–3877.
(6) Yinhu Wang#, Rumana Mowla#, Liwei Guo, Abiodun D. Ogunniyi, Taufiq Rahman, Miguel A. De Barros Lopes, Shutao Ma*, Henrietta Venter*. Evaluation of a series of 2-napthamide derivatives as inhibitors of the drug efflux pump AcrB for the reversal of antimicrobial resistance. Bioorganic & Medicinal Chemistry Letters, 2017, 27, 4: 733-739.
(7) Yinhu Wang, Henrietta Venter, Shutao Ma*. Efflux Pump Inhibitors: A Novel Approach to Combat Efflux-Mediated Drug Resistance in Bacteria. Current Drug Targets, 2016, 17, 6: 702-719.