刘方简介
刘方,1989年6月出生,中国海洋大学医学博士,2018年7月入职suncitygroup太阳集团suncitygroup太阳集团,担任“药剂学”“药剂学实验”“药剂学导论”课程负责人,“药物制剂”课题组负责人,硕士生导师。
研究方向:晶型药物、药物纳米晶、新型制剂的体内外评价研究
联系方式:liufangcnn@163.com
欢迎喜爱药剂学,具有较好物理化学知识基础,不畏失败,善于独立思考的同学加入我们课题团队。
(一)代表性文章:
1. Shu-Yun Hao, Jin-Yang Li, Chong-Qiang Mu, Deng-Shuo Liu, Yu Yang, Yan-Tuan Li, Tie-Min Liu, Xue-Kun Wang, and Fang Liu*. Hepatoprotective Pyrazinamide–Baicalein Cocrystal with a Rare Ratio of 7: 3[J]. Crystal Growth & Design, 2023, 23(2): 885-891.
2. Fang Liu; Ling-Yang Wang; Ming-Chao Yu; Yan-Tuan Li*; Zhi-Yong Wu; Cui-Wei Yan; A new cocrystal of isoniazid-quercetin with hepatoprotective effect: The design, structure, and in vitro/in vivo performance evaluation[J]. European Journal of Pharmaceutical Sciences, 2020, 144: 1-7.
3. Fang Liu, Fu-Bing Jiang, Yan-Tan Li*, Ren-Min Liu, Zhi-Yong Wu. Cocrystallization with syringic acid presents a new opportunity for effectively reducing the hepatotoxicity of isoniazid[J]. Drug Development and Industrial Pharmacy, 2020, 46: 988-995.
4. Fang Liu, Yu Song, Ya-Nan Liu, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan, Drug-bridge-drug ternary cocrystallization strategy for anti-tuberculosis drugs combination. Crystal Growth & Design, 2018, 18: 1283-1286.
5. Fang Liu, Ling-Yang Wang, Yan-Tuan Li*, Zhi-Yong Wu, Cui-Wei Yan, Protective effects of quercetin against pyrazinamide induced hepatotoxicity via cocrystallization strategy of complementary advantages. Crystal Growth & Design, 2018, 18: 3729-3733.
(二) 横纵向课题:
“联用抗结核药物三元共晶的设计、组装及相关性质研究”,国家自然科学青年基金,2022.01-2024.12,30万,主持;
“以改善兼容性为导向的抗结核药物共晶研究”,山东省自然科学青年基金,2021.01- 2023.12,14万,主持;
“以降毒增效为导向的共晶型铂类药物研究”,山东省自然科学基金联合基金,2023.01- 2025.12,15万,主持;
“抗体与小分子药物设计和筛选创新团队”,山东省高等学校青年创新团队/suncitygroup太阳集团光岳学者创新团队;150万,参与;
“原料药固有溶出速率测试平台研发”,横向课题, 2024.04-2026.04,80万,主持;
“解酒护肝泡腾片制备工艺研究开发计划”,横向课题,2021.01-2023.12,30万,主要完成人;
新型多靶点抗肿瘤药物共晶的研发,suncitygroup太阳集团博士启动基金,8万,主持。