基本信息:
姓名:李磊
职称:教授
学历:博士
电子信箱:llee2005@163.com
出生年月:1986.06
研究方向:功能有机分子绿色合成、可见光介导的绿色化学转化、多肽及蛋白分子的氮端修饰
学习及工作经历:
2023.01. - suncitygroup太阳集团 教授
2020.08. - 2022.12. 安徽大学 副教授
2017.09. - 2020.07. 南京大学 博士
2013.07. - 2017.08. 南方科技大学 研究助理
2009.09. - 2012.06. 华东师范大学 硕士
2005.09. - 2009.06. 阜阳师范大学 学士
个人简介:李磊,教授,硕士生导师,山东省泰山学者青年专家,suncitygroup太阳集团光岳学者特聘教授。主要研究方向为有机功能分子转化和可见光介导的光化学反应。近年来,研究工作集中于惰性键活化、可见光促进的官能团转化以及功能有机分子(光、电、生物活性分子)结构性质研究,发展了温和条件下中/大环分子构建新方法,开发了可见光诱导的碳-碳键活化新体系,探索功能有机分子的结构后修饰,揭示惰性有机分子催化转化反应机理。在高水平期刊Sci. Adv.、Nat. Commun.、Org. Lett.、Chin. Chem. Lett.、Mat. Res. Lett.、Chem. Commun.、Org. Chem. Front.等发表论文40余篇。主持国家自然科学基金青年项目、suncitygroup太阳集团高层次人才启动基金、企业合作项目各一项,参与多个国家自然科学基金项目的研究工作,连续指导三届全国大学生化学实验创新设计大赛获赛区一等奖一项、二等奖两项。
发表论文:
Lei Li,† Zhong-Liang Li,† Qiang-Shuai Gu, Na Wang, Xin-Yuan Liu*, A remote C–C bond cleavage–enabled skeletal reorganization: Access to medium-/large-sized cyclic alkenes, Sci. Adv. 2017, 3, e1701487.
Lei Li,† Zhong-Liang Li, † Fu-Li Wang, Zhen Guo, Yong-Feng Cheng, Na Wang, Chao Fang, Jingjiang Liu, Chunhui Hou, Bin Tan, Xin-Yuan Liu*, Remote Radical Aryl Migration Enables Diversity-Oriented Synthesis of Structurally Diverse Medium/Macro- or Bridged-Rings, Nat. Commun. 2016, 7, 13852.
Hao Jia,† Xuening Sun,† Xinmiao Meng, Min Wu, Aisen Li, Miao Yang , Chengyuan Wang*, Jiaxiang Yang*, Kai Wang, Qian Li*, Lei Li*, Developing piezochromic luminescent materials via regioselective cyanation of naphthalimide–cyanostilbene derivatives, Mater. Chem. Front., 2024, 8, 3064.
Zhenzhen Gao*; Xiaoming Zhou; Baoshen Nie; Hanchong Lu; Xiaotong Chen; Jiahui Wu; Xuekun Wang; Lei Li*, Synthesis of 3,4-Disubstituted Maleimide Derivatives via Phosphine-Catalyzed Isomerization of α-Succinimide-Substituted Allenoates Cascade γ′-Addition with Aryl Imines, Int. J. Mol. Sci. 2024, 25, 6916.
Zhenzhen Gao*,†, Xiaoming Zhou†, Dandan Liu, Baoshen Nie, Hanchong Lu, Xiaotong Chen, Jiahui Wu, Lei Li*, Xuekun Wang*, Phosphine-Catalyzed γ′-Carbon 1,6-Conjugate Addition of α-Succinimide Substituted Allenoates with Para-Quinone Methides: Synthesis of 4-Diarylmethylated 3,4-Disubstituted Maleimides, Molecules 2024, 29, 2593.
Min Hong*, Juan Wang, Haobin Chen, Jiayu Qi, Qinghong Ji, Xiaoyan Liu, Qiaoli Yue, Lei li*, Shuang Cheng*, Synthesis and biological evaluation of folic acid-rotenol conjugate as a potent targeted anticancer prodrug, Eur. J. Pharmacol. 2024, 970, 176482.
Xinmiao Meng, Lin Wei, Min Wu, Aisen Li, Lei Li*, Kai Wang*, Qian Li*, Resolving multiple emissions of zero-dimensional heterometallic halide hybrid via pressure-triggered antenna effect, Mater. Res. Lett. 2024, 12, 417.
Yan-Rui Zhao , Lei Li∗, Jun Xuan∗, Catalyst-Free, Multicomponent Reaction of Iodonium Ylides, Nitrosoarenes, and Olefins for the Synthesis of Isoxazolidine Derivatives, Synlett 2023, 34, 2022.
Yan-Rui Zhao, Lei Li*, Jun Xuan*, Direct Synthesis of Indolines via Cyclization of Tertiary Aryl Amines with Iodonium Ylides under Sole Visible Light Irradiation, Adv. Synth. Catal. 2023, 365, 110.
Hai-Bing Ye, Xu-Yu Zhou, Lei Li*, Xiang-Kui He, Jun Xuan*, Photochemical Synthesis of Succinic Ester-Containing Phenanthridines from Diazo Compounds as 1,4-Dicarbonyl Precursors, Org. Lett. 2022, 24, 6018.
Bao-Gui Cai, Qian Li, Qiong Zhang*, Lei Li*, Jun Xuan*, Synthesis of trisubstituted hydroxylamines by visible light-promoted multicomponent reaction, Org. Chem. Front. 2021, 8, 5982.
Shuang-Jing Zhou, Bao-Gui Cai, Chun-Xia Hu, Xu Cheng, Lei Li,* Jun Xuan,* Visible light and base promoted O-H insertion/cyclization of para-quinone methides with aryl diazoacetates: An approach to 2,3-dihydrobenzofuran derivatives, Chin. Chem. Lett. 2021, 32, 2577.
Juan Lu, Lei Li,* Xiang-Kui He, Guo-Yong Xu,* Jun Xuan,* Visible Light-Promoted Sulfoxonium Ylides Synthesis from Aryl Diazoacetates and Sulfoxides, Chin. J. Chem. 2021, 39, 1646.
Lei Li, Lili Fang, Jin Zhu*, Visible Light-Mediated Intermolecular Radical Conjugate Addition for the Construction of Vicinal All-Carbon Quaternary Centers, Org. Lett. 2020, 22, 5401.
Lei Li, Shan Guo, Qi Wang, Jin Zhu*, Acyl Radicals from Benzothiazolines: Synthons for Alkylation, Alkenylation, and Alkynylation Reactions, Org. Lett. 2019, 21, 5462.